Mathematical Modeling of Biological Systems
and Nonlinear Dynamics
Course on Optical Tweezers and Applications
to Cell Biology
(Topics in Atomic, Molecular and Optical Physics)
H. Moyses Nussenzveig
Second Semester 2002.
The COPEA Optical Tweezers Laboratory just
started to operate and the idea of the class is to learn together
about the research oportunities.
Optical Tweezers - what they are and how they work
Mechanical forces in the cellular scale
Mechanical Properties of Proteins
Thermal forces and diffusion
Estruture of citoskeleton filaments
Polimerization of filaments
Force generation by filaments
Structure and properties of motor proteins (molecular motors)
Molecular basis of muscular contraction
Jonathon Howard, "Mechanics of Motor Proteins and the Cytoskeleton",
Sinauer Associates (2001).
Dennis Bray, "Cell Movements", 2nd ed., Garland Publishing (2001).
David Boal, "Mechanics of the Cell", Cambridge University Press (2002).